Potential biomarkers for adult acute myeloid leukemia minimal residual disease assessment searched by serum peptidome profiling
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چکیده
منابع مشابه
Minimal residual disease quantitation in acute myeloid leukemia.
The prognosis for patients with acute myeloid leukemia (AML) is heterogeneous. A minority of patients have clinical and biologic features associated with a very high risk of relapse. For the remaining patients, no clear prognostic factors can be identified at diagnosis. The degree of treatment response is likely to be an informative predictor of outcome for these patients. Modern assays to dete...
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Acute myeloid leukemia (AML) is a curable malignancy, but its cure rate remains disappointingly low. Accurate quantitation of residual AML cells would allow individualization of therapy and thereby increase the likelihood of cure for each patient. Techniques that are being studied for residual disease detection include molecular assays for abnormalities that are present in subsets of AML patien...
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AbSTRACT In acute myeloid leukaemia (AML) alterations in apoptotic pathways are crucial for treatment outcome, resulting either in refractoriness or in Minimal Residual Disease (MRD). The apoptosis characteristics of MRD cells may differ from those at diagnosis and thereby determine the adequacy of further treatment. Such characteristics are largely unknown, since studies hereto are hampered by...
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background: minimal residual disease (mrd) tests provide early identification of hematologic relapse and timely management of acute myeloid leukemia (aml) patients. approximately, 50% of aml patients do not have clonal chromosomal aberrations and categorize as a cytogenetically normal acute myeloid leukemia (cn-aml). about 60% of adult cn-aml has a mutation in exon 12 of npm1 gene. this mutatio...
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It sounds good when knowing the minimal residual disease in acute leukemia in this website. This is one of the books that many people looking for. In the past, many people ask about this book as their favourite book to read and collect. And now, we present hat you need quickly. It seems to be so happy to offer you this famous book. It will not become a unity of the way for you to get amazing be...
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ژورنال
عنوان ژورنال: Proteome Science
سال: 2013
ISSN: 1477-5956
DOI: 10.1186/1477-5956-11-39